What is it about?
Toxigenic isolates carried the El Tor CTX prophage and toxin-coregulated pilus A gene (tcpA), as well as the Vibrio seventh pandemic island I (VSP-I) and VSP-II. Among a subset of 42 toxigenic isolates screened by MLST, all were in the same sequence type, nontoxigenic isolates, generally lacked VSP-I and -II, and fell within13 additional sequence types.
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Why is it important?
Our data suggest that toxigenic O139 isolates from widely divergent geographic locations, while showing some diversity, have maintained a relatively tight clonal structure across a 20-year time span. Nontoxigenic isolates, in contrast, exhibited greater diversity, with multiple clonal lineages, than did their toxigenic counterparts.
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This page is a summary of: A Molecular Surveillance Reveals the Prevalence of Vibrio cholerae O139 Isolates in China from 1993 to 2012, Journal of Clinical Microbiology, January 2014, ASM Journals,
DOI: 10.1128/jcm.03354-13.
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