The Seventh Pandemic Vibrio cholerae O1 El Tor Isolate in China

What is it about?

A total of 330 clinical Vibrio cholerae O1 serogroups from China dating between 1961 and 2010 were investigated. By phenotypic biotyping and genetic analysis, during the seventh pandemic of V. cholerae O1 in China, the isolates of hybrid biotype (mixed classical phenotypes) were present during the entire1961-2010 period, while El Tor genetic shifts appeared in 1992 and replaced the prototype El Tor from 2002 to 2010.

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Why is it important?

The El Tor variants have replaced the prototype seventh pandemic El Tor variant in China, which is consistent with the shift in most countries in Asia and Africa.