What is it about?

Isolates of Paracoccidioides brasiliensis and Paracoccidioides lutzii, previously characterized by molecular techniques, were identified for the first time by matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS).

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Why is it important?

MALDI-TOF MS is a new tool for differentiating species of the genus Paracoccidioides.

Perspectives

MALDI-TOF MS can be the method of choice for species differentiation of the genus Paracoccidioides, benefiting clinical and laboratorial studies aiming to determine possible differences between the diseases caused by these two species.

Danilo Yamamoto Thomaz
University of São Paulo

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This page is a summary of: Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Differentiation of the Dimorphic Fungal Species Paracoccidioides brasiliensis and Paracoccidioides lutzii, Journal of Clinical Microbiology, January 2015, ASM Journals,
DOI: 10.1128/jcm.02847-14.
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