What is it about?
We described the impact of the capsule size for Cryptococcus neoformans and Cryptococcus gattii identification at the species level by Bruker matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS).
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Why is it important?
After experimental capsule size modulation, we observed that reducing the capsule size resulted in improved identification by Bruker MALDI-TOF MS across all of the reference strains analyzed.
Perspectives
Reducing the capsule size may improve mass spectra quality, and consequently, Cryptococcus species ID using this technology may be achieved.
Danilo Yamamoto Thomaz
University of São Paulo
Read the Original
This page is a summary of: Does the Capsule Interfere with Performance of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Identification of Cryptococcus neoformans and Cryptococcus gattii?, Journal of Clinical Microbiology, December 2015, ASM Journals,
DOI: 10.1128/jcm.02635-15.
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