What is it about?
This paper focuses on the detection of extended-spectrum beta-lactamases (ESBLs), AmpC beta-lactamases and carbapenemases in gram-negative pathogens.
Featured Image
Why is it important?
It is important to detect ESBLs, AmpCs and carbapenemases because they can cause treatment failures which cannot reliably be predicted from routine antibiotic susceptibility tests. Therefore special tests are required to detect these resistance mechanisms.
Perspectives
It is critical that ESBLs, AmpC beta-lactamases, and carbapenemases are promptly and accurately detected. For this to happen, laboratories must be adequately funded and staffed and properly equipped and keep abreast of new developments. If microbiology laboratories are incapable of providing the standard of excellence that is needed, many patients will suffer, and resistant pathogens will spread, leading to uncontrolled antibiotic resistance.
Dr Kenneth S Thomson
University of Louisville
Read the Original
This page is a summary of: Extended-Spectrum- -Lactamase, AmpC, and Carbapenemase Issues, Journal of Clinical Microbiology, February 2010, ASM Journals,
DOI: 10.1128/jcm.00219-10.
You can read the full text:
Contributors
The following have contributed to this page
