What is it about?
Nucleotide sugars are substrates for biosynthesis of diverse polysaccharides and sugar-carrying molecules. UDP-glucose is one of the important and universal nucleotide sugars. GalU-type enzyme has been the bacterial standard for production of UDP-glucose. Now, CugP-type enzyme is the second standard and widely distributed to cyanobacteria, phototrophic prokaryotes.
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Why is it important?
It is important for understanding of evolutionary background for sugar metabolism. It is also important for engineering of photosynthetic production of biomolecules.
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This page is a summary of: CugP Is a Novel Ubiquitous Non-GalU-Type Bacterial UDP-Glucose Pyrophosphorylase Found in Cyanobacteria, Journal of Bacteriology, April 2014, ASM Journals,
DOI: 10.1128/jb.01591-14.
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