What is it about?

In this study, a tetH knockout (ΔtetH) mutant and a tetH overexpression strain were constructed and characterized. This study not only provided substantial base for studying the function of tetH gene, but also could serve as a model to clarify other candidate genes involved in sulfur oxidation in this organism.

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Why is it important?

Ii is the first time to addree the function of the tetH by knocking it out, as well as its overexpression.

Perspectives

This study not only provided substantial base for studying the function of tetH gene, but also could serve as a model to clarify other candidate genes involved in sulfur oxidation in this extremely acidophilic organism.

Professor Xiangmei Liu
Shandong University

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This page is a summary of: Construction and Characterization of tetH Overexpression and Knockout Strains of Acidithiobacillus ferrooxidans, Journal of Bacteriology, April 2014, ASM Journals,
DOI: 10.1128/jb.01472-13.
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