What is it about?
Chlamydia pneumoniae and Chlamydiae trachomatis are human pathogenic bacteria which cause a number of different important human diseases. In our work we elucidate the mechanisms by which these pathogens bind to human cells and infect them.
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Why is it important?
Understanding the molecular cross talk between the chlamydial pathogens and its host cell is fundamental for developing a vaccine which currently is not available.
Perspectives
During the last few years we have identified several chlamydial proteins involved in the early steps of the infection. These proteins are currently being tested for their capacity to act as vaccine. Much more work is required to come to a complete understanding of these processes. However, within the next few years a vaccine candidate should be within reach.
Professor Johannes H Hegemann
Heinrich-Heine-Universitat Dusseldorf
Read the Original
This page is a summary of: Characterization of the Interaction between the Chlamydial Adhesin OmcB and the Human Host Cell, Journal of Bacteriology, September 2013, ASM Journals,
DOI: 10.1128/jb.00780-13.
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