What is it about?
Alicycliphilus denitrificans strain BC and A. denitrificans strain K601T degrade cyclic hydrocarbons. These strains have been isolated from a mixture of wastewater treatment plant material and benzene-polluted soil and from a wastewater treatment plant, respectively, suggesting their role in bioremediation of soil and water. Although the strains are phylogenetically closely related, there are some clear physiological differences. The hydrocarbon cyclohexanol, for example, can be degraded by strain K601T but not by strain BC. Furthermore, both strains can use nitrate and oxygen as an electron acceptor, but only strain BC can use chlorate as electron acceptor. To better understand the nitrate and chlorate reduction mechanisms coupled to the oxidation of cyclic compounds, the genomes of A. denitrificans strains BC and K601T were sequenced. Here, we report the complete genome sequences of A. denitrificans strains BC and K601T.
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Why is it important?
Determination of the genome sequences of different Alicycliphilus strains helps to better understand their capacity in degrading cyclic hydrocarbons in soil and water.
Perspectives
Elucidation of the genome sequences of Alicycliphilus denitrificans strains BC and K601T allows the identification of key genes involved in chlorate reduction in strain BC and the identification of genes involved in the degradation of cyclohexanol in strain K601T. Furthermore, this study will help to elucidate the oxygenase-mediated pathways responsible for the degradation of benzene and toluene in Alicycliphilus denitrificans.
Professor Willem J.H. van Berkel
Wageningen University
Read the Original
This page is a summary of: Genome Sequences of Alicycliphilus denitrificans Strains BC and K601T, Journal of Bacteriology, July 2011, ASM Journals,
DOI: 10.1128/jb.00365-11.
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