What is it about?

The early induction of IL-25 in the intestine in response to T. spiralis infection regulates Th9 immune responses and promotes protective immunity by driving intestinal mastocytosis and Paneth cell function.

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Why is it important?

This study relates the role of IL-25 and Th9 immune response in helminth parasite infection and provides novel insights into the complexity of immune response to helminth infection that can be important for designing better approaches to prevent parasitic infection.

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This page is a summary of: Interleukin-25 (IL-25) Promotes Efficient Protective Immunity against Trichinella spiralis Infection by Enhancing the Antigen-Specific IL-9 Response, Infection and Immunity, July 2013, ASM Journals,
DOI: 10.1128/iai.00646-13.
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