What is it about?
This paper describes a method to construct fungal strains having partial chromosomal duplication. The constructed chromosomal duplication strains possess about 1Mb of tandem arrayed chromosomal duplication at targeted region.
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Why is it important?
Partial chromosomal duplication in fungal strains allows phenotypic change result from gene dosage effect of the duplicated chromosomal region.
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This page is a summary of: Targeted Tandem Duplication of a Large Chromosomal Segment in Aspergillus oryzae, Applied and Environmental Microbiology, May 2014, ASM Journals,
DOI: 10.1128/aem.00300-14.
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