What is it about?
Naturally-occuring Hepatitis C Virus Resistance profiles to Direct-Acting Antivirals (DAA) is here described for all HCV genotypes in the largest dataset available to date.
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Why is it important?
Because DAA treatment is extending to all HCV genotypes, it is important to know the natural resistance profile of non-1 genotype viruses to optimize treatment options.
Perspectives
These data can help to further personalize DAA treatment regimes, and to characterize clinically-relevant resistance variants in non-1 HCV genotypes.
F. Xavier López-Labrador
FISABIO-Public Health, Valencia, Spain
Read the Original
This page is a summary of: Comprehensive Screening for Naturally Occurring Hepatitis C Virus Resistance to Direct-Acting Antivirals in the NS3, NS5A, and NS5B Genes in Worldwide Isolates of Viral Genotypes 1 to 6, Antimicrobial Agents and Chemotherapy, February 2016, ASM Journals,
DOI: 10.1128/aac.02776-15.
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