What is it about?
C. elegans infection model is the widely accepted and we utilized this model to found FDA approved molecule diflunisal to inhibit Francisella tularensis live vaccine strain (LVS)
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Why is it important?
Bioagent is now potentially emerging threat and we found a drug that it inhibits Francisella tularensis live vaccine strain (LVS)
Perspectives
We think this is one of the useful findings in order to overcome antibiotic resistance and difficulties in novel drug finding
NAGENDRAN THARMALINGAM
Brown University
Read the Original
This page is a summary of: Characterization of a Francisella tularensis-Caenorhabditis elegans Pathosystem for the Evaluation of Therapeutic Compounds, Antimicrobial Agents and Chemotherapy, June 2017, ASM Journals,
DOI: 10.1128/aac.00310-17.
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