EBV genomes from primary NPC biopsies
What is it about?
This study established a workflow from viral DNA capture and sequencing to de-novo assembly and contig joining and reported eight new EBV genomes isolated from NPC biopsy specimens and revealed diversity on a whole-genome scale among the EBV isolates.
Why is it important?
At least two lineages of EBV strains are revealed. This work provides a platform for genomic sequencing of EBV on a larger scale and may enable a systematic investigation on the role of variations/mutations in the viral genome in the pathogenesis of EBV-associated cancers such as nasopharyngeal carcinoma.
The following have contributed to this page: Dr Alan KS CHIANG
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