AtlA mediating eDNA release contributes to infective endocarditis
What is it about?
Infective endocarditis is a biofilm-related infetious disease and refractory to antibiotic treatment. This study demonstrated the AtlA, autolysin of S. mutans, contributes to bacterial extracellular DNA release, which facilitate to biofilm formation on the damaged valve of experimental endocarditis rats.
Why is it important?
Our finding demonstrated the role of bacterial AtlA and eDNA in the pathogenesis of IE. It provides important important information in the pathogenesis of IE.
The following have contributed to this page: Professor Jean-San Chia and Chiau-Jing Jung
In partnership with: