Specific Properties of Enteropathogenic Escherichia coli Isolates from Diarrheal Patients and Comparison to Strains from Foods and Fecal Specimens from Cattle, Swine, and Healthy Carriers in Osaka City, Japan

  • Lili Wang, Mitsuko Wakushima, Tetsu Aota, Yuka Yoshida, Toshimasa Kita, Tomofumi Maehara, Jun Ogasawara, Changsun Choi, Yoichi Kamata, Yukiko Hara-Kudo, Yoshikazu Nishikawa
  • Applied and Environmental Microbiology, December 2012, ASM Journals
  • DOI: 10.1128/aem.03380-12

Discrimination of human enteropathogenic Escherichia coli

What is it about?

Enteropathogenic Escherichia coli (EPEC), one of the six diarrheagenic E. coli (DEC) pathotypes, is a major cause of diarrheal diseases among young children in developing countries. However, EPEC is prevalent not only patients but healthy peoples, domestic animals, and the products. This study is to know the source of EPEC being virulent to human.

Why is it important?

The present study suggests that the etiologically important EPEC in diarrheal patients could be shared with bovine EPEC. In contrast, the EPEC strains in healthy humans were different from patient strains and some of these were also present in porcine samples.


Professor Yoshikazu Nishikawa
Osaka City University

From the viewpoint of intervention strategy, bovine aEPEC should be the targets to control the infection in human. EPEC strains carried by healthy adults seem not to be serious hazards as the causative agents.

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The following have contributed to this page: Professor Yoshikazu Nishikawa