Interspecific Quorum Sensing Mediates the Resuscitation of Viable but Nonculturable Vibrios

  • Mesrop Ayrapetyan, Tiffany C. Williams, James D. Oliver
  • Applied and Environmental Microbiology, February 2014, ASM Journals
  • DOI: 10.1128/aem.00080-14

What is it about?

This publication demonstrates that bacterial communication through interspecies quorum sensing can resuscitate (or awaken) cells from a dormancy state known as the viable but non-culturable (VBNC) state.

Why is it important?

This study provides new insight into the molecular mechanisms that stimulate resuscitation from the VBNC state and demonstrates that these mechanisms can be targeted to manipulate dormancy dynamics. By maintaining control over dormancy dynamics, we may potentially control the growth of bacteria in chronic and recurrent infections. Furthermore, it can allow for more efficient detection of microorganisms in the environment, food products and culture-negative infections.

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The following have contributed to this page: Professor James D Oliver and Mr Mesrop Ayrapetyan