High Rate of Fecal Carriage of Extended-Spectrum-β-Lactamase-Producing Escherichia coli in Healthy Children in Gipuzkoa, Northern Spain

  • María Fernández-Reyes, Diego Vicente, María Gomariz, Olatz Esnal, Joseba Landa, Eider Oñate, Emilio Pérez-Trallero
  • Antimicrobial Agents and Chemotherapy, January 2014, ASM Journals
  • DOI: 10.1128/aac.01503-13

Faecal carriage of ESBL-producing E. coli in Spanish children

What is it about?

The prevalence and genetic characteristic of extended-spectrum-β-lactamase (ESBL)-producing bacteria in stool samples from 125 healthy children at the ages of 8, 12 and 16 months, was investigated. Molecular characterization of ESBL-encoding genes was performed by multiplex-PCR. A total of 24% of the 125 children and 10.7% of the 318 fecal samples studied yielded ESBL producers. Together the resistance to beta-lactams, 20.6% of isolates were resistant to levofloxacin and other antimicrobials

Why is it important?

About a quarter of healthy children between 8 and 16 months old in northern Spain harbor in their intestines multiresistant (ESBL-producing E. coli) strains. This high carriage rate in healthy children should alert us to the possibility of an increase of clinical infections by these strains.

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The following have contributed to this page: Emilio Pérez-Trallero