What is it about?

In this review, we address the role of glucocorticoid and mineralocorticoid receptors from their long term alterations to their rapid, synaptic effects, and how these influence changes in the stress response.

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Why is it important?

This is important because the stress hormone, cortisol, can lead to both acute and long term changes in neuronal functioning, which may lead to increased anxiety and/or the development of posttraumatic stress disorder.

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This page is a summary of: Stress at the Synapse: Signal Transduction Mechanisms of Adrenal Steroids at Neuronal Membranes, Science Signaling, August 2009, American Association for the Advancement of Science,
DOI: 10.1126/scisignal.286re5.
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