What is it about?

Receptor sensitization and CNS disorders

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Why is it important?

The phenomenon is entailed in neurological and psychiatric disorders.

Perspectives

Dopamine receptor sensitization interplays with multiple CNS disorders; we've developed a new animal model of schizophrenia.

Richard Kostrzewa
East Tennessee State Univ, College of Medicine

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This page is a summary of: Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders, Journal of Pharmacology and Experimental Therapeutics, June 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET),
DOI: 10.1124/jpet.118.247981.
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