What is it about?
The sympathetic nerves control the flow of blood to all parts of the body. Here we show that the peptide orexin, acting in the spinal cord is critical to this process.
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Why is it important?
This work is important because neural control of blood flow and pressure is poorly understood, yet high blood pressure remains a major cause of disease in our society.
Perspectives
The cost, economic and personal, of high blood pressure is one of the most significant challenges in all parts of the world. Amelioration of this problem is vitally important.
Paul Pilowsky
University of Sydney
Read the Original
This page is a summary of: Intrathecal Intermittent Orexin-A Causes Sympathetic Long-Term Facilitation and Sensitizes the Peripheral Chemoreceptor Response to Hypoxia in Rats, Journal of Pharmacology and Experimental Therapeutics, July 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET),
DOI: 10.1124/jpet.116.234443.
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