What is it about?
A new drug has been identified that targets mitochondria and has activity in treating lung cancer. This is a scientific study that accompanies ongoing clinical trials in patients with this disease. The results show why the drug has value in this disease state.
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Why is it important?
This will act as a platform for follow up studies designed to elucidate more about he drug and aid in its development towards FDA approval
Perspectives
New drug development is an important component of cancer treatment. This drug is unusual since many isoflavones do not possess cytotoxic activity. In this case, the drug is unusual and should find a niche in the treament of cancers.
kenneth Tew
Medical University of South Carolina
Read the Original
This page is a summary of: Redox Signaling and Bioenergetics Influence Lung Cancer Cell Line Sensitivity to the Isoflavone ME-344, Journal of Pharmacology and Experimental Therapeutics, June 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET),
DOI: 10.1124/jpet.115.229344.
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