What is it about?
Prolactin is a regulator of hepatic p450 gene expression.
Featured Image
Why is it important?
So far growth hormone has been considered as a main regulator of hepatic p450 gene expresion. This is the first report about the regulatory role of prolactin on hepatic p450 gene expression. P450 is deeply related to drug and steroid metabolism and hyperprolactinemia during pregnancy, lactation or prolactinoma may influence it.
Read the Original
This page is a summary of: Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver, Drug Metabolism and Disposition, March 2017, American Society for Pharmacology & Experimental Therapeutics (ASPET),
DOI: 10.1124/dmd.116.074658.
You can read the full text:
Contributors
The following have contributed to this page
