Dopamine D2Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders

Richard M. Kostrzewa, Karolina Wydra, Malgorzata Filip, Cynthia A. Crawford, Sanders A. McDougall, Russell W. Brown, Dasiel O. Borroto-Escuela, Kjell Fuxe, Raul R. Gainetdinov
  • Journal of Pharmacology and Experimental Therapeutics, June 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)
  • DOI: 10.1124/jpet.118.247981

Dopamine receptor supersensitivity

What is it about?

Receptor sensitization and CNS disorders

Why is it important?

The phenomenon is entailed in neurological and psychiatric disorders.


Richard Kostrzewa (Author)
East Tennessee State Univ, College of Medicine

Dopamine receptor sensitization interplays with multiple CNS disorders; we've developed a new animal model of schizophrenia.

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