What is it about?
For the first time, this study quantitatively differentiate acute and chronic tumor hypoxia using serial PET imaging for 12 patients.
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Why is it important?
Acute and chronic hypoxia has different radiation responses in radiotherapy, thus the differentiation of those 2 types is crucial in dose painting.
Perspectives
Further study for hypoxia modeling at cellular level could disclose the mechanism of hypoxia types and correspondence to radiations.
Kelin Wang
University of Pittsburgh Medical Center Health System
Read the Original
This page is a summary of: Modeling acute and chronic hypoxia using serial images of F18-FMISO PET, Medical Physics, September 2009, Wiley,
DOI: 10.1118/1.3213092.
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