What is it about?

It utilizes the cumulative phase retardation contrast of the PS-OCT, with a slope-based analysis, to distinguish the layers with different birefringence.

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Why is it important?

Birefringence is a property sensitive to collagen organizations in bio-samples. By differentiating the layers with different birefringence, it will enhance the sensitivity of detecting any subtle collagen damage in related diseases, e.g. the osteoarthritis (OA).

Perspectives

It is part of our ongoing project. Seeking proper applications will be of importance. Jones Matrix is more reliable measurement than the cumulative phase retardation, or local phase retardation. To this method, the reliability could be improved by further improve the phase retardation data by compensation, correction, or other ways.

XIN ZHOU
University of British Columbia

Read the Original

This page is a summary of: Slope-based segmentation of articular cartilage using polarization-sensitive optical coherence tomography phase retardation image, Journal of Biomedical Optics, March 2019, SPIE, DOI: 10.1117/1.jbo.24.3.036006.
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