What is it about?
This is a discussion of the question whether proton permeation through Hv1 occur by a pure water wire or if the proton must transiently reside on Asp112 (in human Hv1).
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This page is a summary of: CrossTalk proposal: Proton permeation through HV
1 requires transient protonation of a conserved aspartate in the S1 transmembrane helix, The Journal of Physiology, October 2017, Wiley,
DOI: 10.1113/jp274495.
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