What is it about?
The aim of this meta-analysis was to evaluate the efficacy and safety of duloxetine for management of osteoarthritis knee (OAK) pain.
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Why is it important?
This analysis suggests duloxetine (60/ 120 mg quaque die (QD)), compared with placebo control, resulted in a greater reduction in pain, improved function and patient-rated impression of improvement, and acceptable adverse effects for the treatment of OAK pain after approximately 10-13 weeks of treatment.
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This page is a summary of: Efficacy and Safety of Duloxetine on Osteoarthritis Knee Pain: A Meta-Analysis of Randomized Controlled Trials, Pain Medicine, June 2015, Oxford University Press (OUP),
DOI: 10.1111/pme.12800.
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