What is it about?
We studied BNCT in a model of oral precancer in the hamster cheek pouch. We analyzed tumor development during 8 months. We studied mucositis after BNCT, and also histamine as a possible mucositis treatment. Histamine reduced severe mucositis without compromising BNCT inhibitory effect on the development of new tumors.
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Why is it important?
Mucositis is a well known adverse effect in conventional oncological treatments and in BNCT, which limits treatment, affects patient´s quality of life and sometimes induces tumor development.
Perspectives
Hope this publication encourages the investigation on this topic.
Dr Andrea Monti Hughes
CNEA
Read the Original
This page is a summary of: Histamine reduces boron neutron capture therapy-induced mucositis in an oral precancer model, Oral Diseases, June 2015, Wiley,
DOI: 10.1111/odi.12346.
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