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CC- and TIR-NLRs are the major intracellular immune receptors of plants. We found that multiple TIR-NLRs require 'helpers' from the conserved NLR clade 'NRG1'. In fact, all the TIR-NLRs tested (an also some CC-NLRs) signal at least partially via NRG1.

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This page is a summary of: Diverse NLR immune receptors activate defence via the RPW8‐NLR NRG1, New Phytologist, January 2019, Wiley,
DOI: 10.1111/nph.15659.
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