Angiotensin type 2 receptor gene are associated with ureteropelvic junction obstruction

What is it about?

In this study, we investigated if small and common differences in a gene that forms a protein important for the formation of the kidneys and urinary tract have a relation with a frequent malformation of the kidneys and urinary tract. We found that small variances of these gene are more frequent in children with a obstruction between the kidney and the channel that drains the urine called ureteropelvic junction obstruction.

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Why is it important?

We found that children with an specific malformation of the kidney have small variations in a gene that produces a receptor important for the normal formation of the kidney and urinary tract in Brazilian population.

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