What is it about?
We treated the patients with Parkinson's disease by the electrode-guided stereotaxic brain surgery targeting the thalamus. We monitored electrical brain activities for targeting during the surgery and analyzing the parkinsonian pathology. We proposed a method to quantify the thalamic brain activities representing clinical parkinsonian symptoms, tremor and rigidity.
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Why is it important?
Quantitative relationships between the parkinsonian symptoms and their marker brain activities have not been established. They are important for exploring the evidence-based treatment.
Perspectives
Our clinic is specialized for the stereotaxic brain surgery. Quantifying the symptom-brain relationships will be investigated by using some large population of patients with the informed concent.
Dr Tomokazu Oshima
Neurological Clinic
Read the Original
This page is a summary of: Analytical monitoring of brain activities for thalamotomy related with pathophysiology of parkinsonian motor symptoms, Neurology and Clinical Neuroscience, December 2014, Wiley,
DOI: 10.1111/ncn3.133.
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