What is it about?
Brain surgery treats patients with unwilled movements. The desease is progressive. We have found that the progression is preceded by abnormal activity in the thalamus.
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Why is it important?
The study needed a large population of patients because of individual variety. The specialized surgery clinic founded by Hirotaro Narabayashi in 1958 provided the precious materials of study gathered for 1995-2000. The time delay from abnormality of brain cells to expression of symptoms implicates the contribution of some memory process as a critical future target of research.
Perspectives
Oshima is a member of surgery team of the clinic. His part is to monitor physiological events before, during and after the surgery. When the surgery room was closed by the death of the chief surgion, he accidentally designed the study, conducted analysis and wrote papers for the participant patients and medical staff.
Dr Tomokazu Oshima
Neurological Clinic
Read the Original
This page is a summary of: Parkinsonian thalamic activity represents pathophysiology underlying progression of motor symptoms, Neurology and Clinical Neuroscience, September 2015, Wiley,
DOI: 10.1111/ncn3.12014.
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