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The maturation of the Glu2, Ile1 and Ala1B tRNAs, embedded in the seven rRNA operons of E. coli, has been investigated. The RNase E independent processing pathway utilizes at least six different enzymes and is distinct from other tRNA processing pathways. RNase III is involved in both the separation of the pre-tRNAs from the 30S rRNA and the shortening the trailer sequences. PAP I is required for the exonucleolytic decay of the RNase III cleavage products.

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This page is a summary of: Maturation of the E. coli Glu2, Ile1, and Ala1B tRNAs utilizes a complex processing pathway, Molecular Microbiology, June 2022, Wiley,
DOI: 10.1111/mmi.14949.
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