Escherichia coli induces DNA repair enzymes to protect itself from low‐grade hydrogen peroxide stress

What is it about?

Concentrations of hydrogen peroxide in natural habitats are speculated to be in the low micromolar range. We demonstrate that prolonged exposure to these doses of peroxide can cause lethal amounts of DNA damage. The base excision repair and SOS systems are essential to repair this damage and enable growth during extended peroxide stress.

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