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The Che2 chemosensory proteins from Pseudomonas aeruginosa form an Aer2-mediated complex near the cell pole. Aer2 senses oxygen, which promotes a phosphorylation cascade that results in CheY2/CheD interaction. In the absence of oxygen, Aer2 does not signal and CheD is freed from CheY2 to augment Aer2 methylation and enhance Aer2 signaling.
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This page is a summary of: Deciphering the Che2 chemosensory pathway and the roles of individual Che2 proteins from
Pseudomonas aeruginosa, Molecular Microbiology, October 2020, Wiley,
DOI: 10.1111/mmi.14612.
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