Identification of the Wzx flippase, Wzy polymerase and sugar‐modifying enzymes for spore coat polysaccharide biosynthesis in Myxococcus xanthus

What is it about?

Myxococcus xanthus differentiates to environmentally resistant spores in response to various stresses. Resistance is provided by the spore coat polysaccharide that is synthesized by the ExoA-I proteins, which make up an incomplete Wzx/Wzy pathway for polysaccharide synthesis and export. Here, we identified the Wzx flippase and Wzy polymerase as well as three glycosyltransferase and a polysaccharide deacetylase that are important for formation of the intact spore coat, thus, providing a more complete Exo pathway.

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