Functional studies of aegerolysin and MACPF ‐like proteins in Aspergillus niger

What is it about?

Aegerolysin proteins were already proposed as useful tools in different biotechnological and biomedical applications due to their specific binding to membrane lipids, and their membrane-permeabilization potential in concert with protein partner(s) belonging to a membrane-attack-complex/perforin (MACPF) superfamily. Our functional studies suggest, due to involvement of the sporulation process, their biological role could be in defence against predators in the fungus Aspergillus niger, and probably also in other aspergilli.

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