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Pathogenic microbes often escape immune systems by displaying different versions of important surface molecules in a process known as antigenic variation. We show that the amount of transcription is critical to form an alternative DNA structure and initiate antigenic variation of the bacterial pilus.

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This page is a summary of: Transcriptional initiation of a small RNA, not R‐loop stability, dictates the frequency of pilin antigenic variation inNeisseria gonorrhoeae, Molecular Microbiology, August 2019, Wiley, DOI: 10.1111/mmi.14356.
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