Two binding proteins of the ABC transporter that confers growth of Bifidobacterium animalis subsp. lactis ATCC27673 on β‐mannan possess distinct manno‐oligosaccharide‐binding profiles

What is it about?

This study is describes the molecular basis of the competitive growth of a Bifidobacterium on β-mannans. The efficient growth is mediated by secreted mannanase and a single ABC uptake system with two associated capture proteins that display overlapping manno-oligosaccharide specificities. The structures, biochemical properties and phylogenetics of the transport proteins that support competition on preferred substrates is presented.

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