What is it about?
Legionnaires’ disease is a severe pneumonia caused by the bacterial pathogen Legionella pneumophila. The main pathogenesis system of this bacterium is a syringe like device which translocates effector proteins from the bacterial cell into the host cell. We identified and characterized a new regulatory protein which coordinates the expression of effector proteins during infection.
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Why is it important?
The manuscript describes a new function for single domain response regulators
Read the Original
This page is a summary of: The single-domain response regulator LerC functions as a connector protein in the Legionella pneumophila
effectors regulatory network, Molecular Microbiology, August 2018, Wiley,
DOI: 10.1111/mmi.14101.
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