Insights into transcriptional silencing and anti-silencing in Shigella flexneri : a detailed molecular analysis of the icsP virulence locus

What is it about?

A molecular antagonism involving DNA binding proteins regulates gene expression in many bacteria. Here, we characterize the key elements needed for these regulatory events at a virulence gene locus found in the bacterial pathogen Shigella. The remote location of these elements, relative to the gene they control, is surprising.

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