Spatiotemporally regulated proteolysis to dissect the role of vegetative proteins during Bacillus subtilis sporulation: cell-specific requirement of σH and σA

What is it about?

Developmental processes, such as the formation of a whole individual from a fertilized egg, can involve the interaction between millions of cells and are difficult to study. Spore formation in certain bacteria represents a simple developmental process that involve the interaction between only two cells. We have created a system to block specific activities in only one of the cells required to form a spore, therefore allowing for a better understanding of how the two cells interact.

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