PlpA, a PilZ-like protein, regulates directed motility of the bacterium Myxococcus xanthus

What is it about?

Cells of the rod-shaped bacterium Myxococcus xanthus move on surfaces with controlled directionality. In this study, we identified PlpA, a PilZ-like protein that regulates the direction of motility together with a well-studied regulator, MglA. We showed that PlpA and MglA localize at opposite cell poles, regulate the motility motors oppositely and define the polarity axis of motility.

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