Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds

What is it about?

Antibiotic resistance is a global health problem. We provide evidence that a class of compounds can interact with a key protein involved in biofilm formation and virulence in Francisella sp. This information will help tailor compounds for adjuvant therapies with broad-range antibiotics.

Featured Image