Negative regulation of filamentous growth in Candida albicans by Dig1p

What is it about?

The Dig1 protein of Candida albicans is a negative regulator of various signalling pathways including those for mating, invasion and biofilm formation. The influence of Dig1 on these pathways is primarily mediated through the transcription factors Cph1, Efg1 and Tec1, but the influence of these factors on each of the processes varies significantly, with Cph1 being primarily important for mating, Tec1 for biofilms and invasion, and Efg1 for invasion.

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