A novel RNA polymerase‐binding protein that interacts with a sigma‐factor docking site

What is it about?

During the developmental process of sporulation in Bacillus subtilis a cascade of alternative sigma factors associate with RNA polymerase to direct appropriate gene expression. We report that Fin, a novel RNA polymerase-binding protein produced during sporulation, inhibits the function of the sporulation sigma factor F by competing for binding of the factor to RNA polymerase.

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