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Rre1 is an essential response regulator of a highly conserved two component system in cyanobacteria. We identified 15 Rre1 binding sites in the chromosome of S. elongatus by ChIP on tiling array analysis. Under heat stress, Rre1 was phosphorylated by Hik34, which activated major chaperone genes and the group 2 sigma factor gene rpoD2, which, in turn, may propagate a genome-wide transcriptional response.
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This page is a summary of: Conserved two-component Hik34-Rre1 module directly activates heat-stress inducible transcription of major chaperone and other genes inSynechococcus elongatusPCC 7942, Molecular Microbiology, February 2017, Wiley,
DOI: 10.1111/mmi.13624.
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