Structural basis for Myf and Psa fimbriae-mediated tropism of pathogenic strains ofYersiniafor host tissues

What is it about?

Pathogenic yersiniae assemble two homologous fimbrial adhesins, Myf and Psa. We discovered Myf-specific receptors and determined the structural basis for receptor recognition by Myf and Psa. The results suggest that both adhesins play an important role in the tissue tropism of yersiniae, but mediate attachment to different tissues and facilitate different routes of yersiniae transmission.

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