What is it about?
This paper examines the expression levels of 6 candidate microRNAs using TaqMan assays in oral squamous cell carcinoma samples from south India. This is the first study to report the association of miR-155 with tobacco chewing and the downregulation of miR-125b-2* in oral carcinoma.
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Why is it important?
The etiology, pathogenesis and molecular profile of Indian oral carcinoma is quite different from the world oral cancer population. MicroRNA expression studies from India are required to help develop miRNA biomarkers for early diagnosis and reduce the heavy incidence of oral carcinoma.
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This page is a summary of: Altered levels of miR-21, miR-125b-2*, miR-138, miR-155, miR-184, and miR-205 in oral squamous cell carcinoma and association with clinicopathological characteristics, Journal of Oral Pathology and Medicine, December 2014, Wiley,
DOI: 10.1111/jop.12300.
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